Sperm DNA has a significant effect on the embryo quality and the success of the fertility treatments such as intrauterine insemination (IUI) or in vitro fertilization (IVF).. DNA Fragmentation Index (DFI) testing is a diagnostic method that is used to measure the amount of damaged DNA within sperm cells. It calculates the percentage of sperm with fragmented or damaged DNA. Assessment of Sperm Quality: DFI testing provides better information regarding sperm quality and sperm health apart from the basic semen parameters like count, motility, and morphology. High levels of DNA fragmentation can impact fertility, even if other sperm parameters are normal. Helps in Guiding Treatment Decisions: DFI testing helps fertility experts recommend and plan appropriate treatment options, such as ICSI, or use advanced sperm selection techniques such as Magnetic Activated Cell Sorting (MACS) or Microfluidic Sperm Sorting.
High DNA fragmentation results in low fertilization rates, poor embryo quality, and increased miscarriage rates. DFI testing offers valuable insights into sperm DNA integrity, that can help in personalizing the treatment strategies to increase the chances of a successful healthy pregnancy. It is a good option for couples facing unexplained infertility, a history of recurrent pregnancy loss, and failed IVF or ICSI cycles.
With over 15 years of experience and success, Oasis Fertility is the most trusted fertility clinic chain in India. With our clinical expertise and personalized treatments, we have helped many couples have over 1,00,000 healthy babies. We provide comprehensive fertility care with an ethical and transparent approach, ensuring the best possible outcomes.
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